40. Asymmetric deoxygenative difunctionalization of 1,2-dicarbonyl compounds enabled by phosphinite and chiral salen-molybdenum catalyst synergy.
Yu, Y.-Z.†; Li, J.-T.†; Yin, Y.-Q.; Zhuo, C.-X.*
Angew. Chem. Int. Ed. 2026, e2472486.
(Selected as ''hot paper'')
(†Both authors contributed equally)
39. Vicinal dicarbonyl reprogramming via molybdenum-catalyzed formal C(O)−C(O) bond cleavage.
Shi, X.-N.†; Wang, J.-L.†; Chen, Z.†; Wang, D.-K.†; Wu, G.-Y.; Peng, J.-M.; Qi, X.*; Zhuo, C.-X.*
J. Am. Chem. Soc. 2026, 148, 11274-11283.
(†These authors contributed equally)
Highlighted bySynfacts 2026, 22, 523.
(Selected as Synfact of the month)
38. Synthesis of meta-substituted benzenes via Mo-Catalyzed intermolecular deoxygenative coupling of ynones and allylic amines.
Yu, Y.-Z.; Fang, G.; Su, H.-Y.; Zhuo, C.-X.*
Org. Synth. 2025, 102, 381-397.
(Invited contribution)
37. Divergent synthesis of 2-quinolinones and indolin-3-ones via Mo-catalyzed controllable carbonyl deoxygenative coupling and formal deoxygenative N—H insertion reactions.
Yao, J.-S.†; Su, X.†; Yu, Y.-Z.; Wu, J.-B.; Qu, S.*; Zhuo, C.-X.*
Chin. J. Chem. 2025, 43, 1538-1546.
(†Both authors contributed equally)
36. Synthesis of 3,5-disubstituted anilines via sequential Mo-catalyzed deoxygenative benzene formation and Pd-catalyzed amination reactions.
Fang, G.†; Yu, Y.-Z.†; Zhuo, C.-X.*
Synthesis 2025, 57, 1922-1927.
(†Both authors contributed equally)
(Invited contribution as a Feature Article)
35. Anilines formation via molybdenum-catalyzed intermolecular reaction of ynones with allylic amines.
Yu, Y.-Z.; Su, H.-Y. (本科生); Zhuo, C.-X.*
Angew. Chem. Int. Ed. 2024, e202412299.
34. Recent advances in molybdenum catalyzed asymmetric organic transformations.
Wang, J.-L.†; Li, J.-T.†; Wu, G.-Y.; Zhuo, C.-X.*
Trends Chem. 2024, 6, 487-501.
(†Both authors contributed equally)
(Invited contribution to the Special issue: Emerging leaders in chemistry)
Highlighted by Meet our emerging leaders in chemistry – part II.Trends Chem. 2024, 6, 409-414.
33. Catalytic intermolecular deoxygenative coupling of carbonyl compounds with alkynes by a Cp*Mo(II)-catalyst.
Wang, J.-L.†; Wu, G.-Y.†; Luo, J.-N.; Liu, J.-L.; Zhuo, C.-X.*
J. Am. Chem. Soc. 2024, 146, 5605-5613.
(†Both authors contributed equally)
Highlighted by Synfacts 2024, 20, 502.
32. Modular access to diverse amphoteric α-boryl aldehydes or borylated heterocycles via photoredox catalysis.
Li, J.-T.; Fang, G.; Wu, G.-Y.; Zhuo, C.-X.*
ACS Catal. 2023, 13, 12648−12655.
(Among the top 20 most downloaded articles in October 2023)
31. Molybdenum-catalyzed carbonyl-carbonyl olefination reaction for heterocycle syntheses.
Dong, Y.-Q.†; Shi, X.-N.†; Cao, L.-Y.†; Bai, J.; Zhuo, C.-X.*
Org. Chem. Front. 2023, 10, 3544-3552.
(†These authors contributed equally.)
30. Modular access to meta-substituted benzenes via Mo-catalyzed intermolecular deoxygenative benzene formation.
Yu, Y.-Z.; Bai, J.; Peng, J.-M.; Yao, J.-S.; Zhuo, C.-X.*
J. Am. Chem. Soc. 2023, 145, 8781-8787.
(Selected as JACS Supplementary Cover)
(Among the top 20 most downloaded articles in April 2023)
Highlighted by Org. Process Res. Dev. 2023, 27, 993.
Highlighted by Synfacts 2023, 19, 0621.
29. Synthesis of 2-boryl allylboronates by a bimetallic platinum/zinc-promoted diborylation of propargylic amines.
Shi, X.-N.; Wang, J.-L.; Wu, J.-B.; Zhuo, C.-X.*
(Invited contribution to the Special Edition Thieme Chemistry Journals Awardees 2022)
28. Catalytic asymmetric deoxygenative cyclopropanation reactions by a chiral salen-Mo catalyst.
Cao, L.-Y.; Wang, J.-L.; Wang, K.; Wu, J.-B.; Wang, D.-K.; Peng, J.-M.; Bai, J.; Zhuo, C.-X.*
J. Am. Chem. Soc. 2023, 145, 2765-2772.
(Selected as JACS Supplementary Cover)
Highlighted by Synfacts 2023, 19, 358.
27. Molybdenum-catalyzed intermolecular deoxygenative cross-coupling reactions of 1,2-diketones with α-ketoamides.
Dong, Y.-Q.†; Wang, K.†; Zhuo, C.-X.*
ACS Catal. 2022, 12, 11428−11435.
(†Both authors contributed equally.)
26. Stereoselective intermolecular radical cascade reactions of tryptophans or ɤ-alkenyl-α-amino acids with acrylamides via photoredox catalysis.
Li, J.-T.;Luo, J.-N.;Wang, J.-L.; Wang, D.-K.; Yu, Y.-Z.; Zhuo, C.-X.*
25. Catalytic deoxygenative cyclopropanation of 1,2-dicarbonyl or monocarbonyl compounds via molybdenum catalysis.
Wang, J.-L.; Zhuo, C.-X.*
(Invited Synpacts highlight)
24. Molybdenum-catalyzed deoxygenative cyclopropanation of 1,2-dicarbonyl or mono-carbonyl compounds.
Cao, L.-Y.; Luo, J.-N.; Yao, J.-S.; Wang, D.-K.; Dong, Y.-Q.; Zheng, C.; Zhuo, C.-X.*
Angew. Chem. Int. Ed. 2021, 60,15254–15259.
Highlighted by Nature Catalysis 2021, 4, 347. & Synfacts 2021, 17, 906.
23. Catalysis-based total syntheses of pateamine Aand DMDA-Pat A.
Zhuo, C.-X.;Fürstner, A.*
J. Am. Chem. Soc.2018,140,10514–10523.
Highlighted by: Synfacts 2018 , 14 , 1114.
(Among the top 20 most downloaded articles in September, 2018)
22. Concise synthesis of a pateamine A analogue with in vivo anticancer activity based on an iron catalyzed pyrone ring-opening/cross coupling.
Zhuo, C.-X.; Fürstner, A. *
Angew . Chem . Int . Ed .2016 ,55 ,6051-6056.
21. Enantioselective synthesis of pyrrole fused piperazine and piperazinone derivatives via Ir-catalyzed asymmetric allylic amination.
Zhuo, C.-X.; Zhang, X.; You, S.-L.*
ACS Catal. 2016, 6, 5307−5310.
Highlighted by: Synfacts 2016,12, 1043.
20. Enantioselective construction of spiroindolines with three contiguous stereogenic centers and chiral tryptamine derivative via the reactive spiroindolenine intermediates.
Zhuo, C.-X.; Zhou, Y.; Cheng, Q.; Huang, L.; You, S.-L.*
Angew.Chem.Int.Ed. 2015, 54, 14146-14149.
Highlighted by: Synfacts 2016,12, 151.
19. Enantioselective synthesis of pyrrole based spiro- and polycyclic derivatives via Ir-catalyzed asymmetric allylic dearomatization and controllable migration reactions.
Zhuo, C.-X.; Cheng, Q.; Liu, W.-B.; Zhao, Q.; You, S.-L.*
Angew.Chem.Int.Ed. 2015,54, 8475-8479.
Highlighted by: Synfacts,11, 944.
18. Highly regio- and enantioselective synthesis of poly-substituted 2H-pyrroles via Pd-catalyzed intermolecular asymmetric allylic dearomatization of pyrroles.
Zhuo, C.-X.; Zhou, Y.;You, S.-L.*
J. Am. Chem. Soc. 2014,136, 6590-6593.
Highlighted by: J. Am. Chem. Soc. Spotlights (J. Am. Chem. Soc. 2014,136, 6511.)&Synfacts 2014,10, 820.&Organic Chemistry Portal. Highlighted by the highlight module located on the homepage of JACS(May 5, 2014 – May 15, 2014.)
17. Transition-metal catalyzed asymmetric allylic dearomatization reactions.
Zhuo, C.-X.; Zheng, C.;You, S.-L.*
Acc. Chem. Res. 2014, 47, 2558-2573.
16. Palladium-catalyzed intermolecular allylic dearomatization reaction ofa-substituted-β-naphthol derivatives: scope and mechanistic investigation.
Zhuo, C.-X.;You, S.-L.*
Adv. Synth. Catal. 2014, 356, 2020-2028.
15. Palladium-catalyzed intermolecular asymmetric allylic dearomatization reaction of naphthol derivatives.
Zhuo, C.-X.;You, S.-L.*
Angew.Chem.Int.Ed. 2013, 52, 10056-10059.
Highlighted by：Synfacts 2013, 9, 1308.&Chin. J. Org. Chem. 2013, 33, 2440.
14. Enantioselective functionalization of indoles and pyrroles via an in-situ formed spiro-intermediate.
Zhuo, C.-X.; Wu, Q.-F; Zhao, Q.; Xu, Q.-L.; You, S.-L.*
J. Am. Chem. Soc. 2013,135, 8169-8172.
Highlighted by: Synfacts 2013, 9, 874.
13. Catalytic asymmetric dearomatization reactions.
Zhuo, C.-X.; Zhang, W.*; You, S.-L.*
Angew. Chem. Int. Ed. 2012, 51, 12662-12686.
12. Asymmetric dearomatization of pyrroles via Ir-catalyzed allylic substitution reaction: enantioselective synthesis of spiro-2H-pyrroles.
Zhuo, C.-X.; Liu, W.-B.; Wu, Q.-F.; You, S.-L.*
11. Mechanistic insights into the Pd-catalyzed intermolecular asymmetric allylic dearomatization of multisubstituted pyrroles: understanding the remarkable regio- and enantioselectivity.
Zheng, C.*;Zhuo, C.-X.; You, S.-L.*
J. Am. Chem. Soc. 2014, 136, 16251-16259.
10. An iridium(I) N-heterocyclic carbene complex catalyzes asymmetric intramolecular allylic amination reactions.
Ye, K.-Y.; Cheng, Q.;Zhuo, C.-X.; You, S.-L.*
Angew. Chem. Int. Ed. 2016, 55, 8113-8116.
9. Highly efficient synthesis and stereoselective migration reactions of chiral five-membered aza-spiroindolenines: scope and mechanistic understanding.
Wu, Q.-F;Zheng, C.*;Zhuo, C.-X.; You, S.-L.*
8. Intermolecular dearomatization reaction of pyrroles promoted by silica gel.
Zhou, Y.;Zhuo, C.-X.; Gu, Q.; You, S.-L.*
Adv. Synth. Catal. 2015,357, 912-916 (VIP).
7. Asymmetric dearomatization of β-naphthols through an amination reaction catalyzed by a chiral phosphoric acid.
Wang, S.-G.; Yin, Q.;Zhuo, C.-X.; You, S.-L.*
Angew. Chem. Int. Ed. 2015, 54, 647-650.
6. Ruthenium-catalyzed intramolecular allylic dearomatization/migration reaction of indoles and pyrroles.
Yang, Z.-P.;Zhuo, C.-X.; You, S.-L.*
Adv. Synth. Catal. 2014, 356, 1731-1734.
5. Enantioselective synthesis ofN-allylindoles via palladium-catalyzed allylic amination/oxidation of indolines.
Zhao, Q.;Zhuo, C.-X.; You, S.-L.*
RSC Adv. 2014, 4, 10875-10878.
4. Highly enantioselective synthesis of tetrahydrocarbolines via iridium-catalyzed intramolecular Friedel-Crafts type allylic alkylation reactions.
Xu, Q.-L.;Zhuo, C.-X.; You, S.-L.*
Org. Lett. 2013,15, 5909-5911.
3. Ir-catalyzed allylic alkylation reaction with N-aryl phosphoramidite ligands: scope and mechanistic studies.
Liu, W.-B.; Zheng, C.;Zhuo, C.-X.; Dai, L.-X.; You, S.-L.*
J. Am. Chem. Soc. 2012,134, 4812-4821.
2. Iridium-catalyzed intramolecular asymmetric allylic dearomatization of phenols.
Wu, Q.-F.; Liu, W.-B.;Zhuo, C.-X.; Rong, Z.-Q.; Ye, K.-Y.; You, S.-L.*
Angew.Chem.Int.Ed. 2011, 50, 4455-4458.
1. Synthesis of Cyclopropane-containing Building Blocks via Ir-Catalyzed Enantioselective Allylic Substitution Reaction.
Xia, J.-B.;Zhuo, C.-X.;You, S.-L.*
Chin. J. Chem. 2010, 28, 1525-1528.
1. You, S.-L.; Zhuo, C.-X.; Liu, W.-B. Chirality phosphine nitrogen compound containing N-aryl as well as synthetic method and application thereof. CN103087106 B.