2024

36. Synthesis of 3,5-disubstituted anilines via sequential Mo-catalyzed deoxygenative benzene formation and Pd-catalyzed amination reactions.

Fang, G.; Yu, Y.-Z.; Zhuo, C.-X.*

Synthesis 2024, asap

(Both authors contributed equally)

(Invited contribution as a Feature Article)


35.
Anilines formation via molybdenum-catalyzed intermolecular reaction of ynones with allylic amines.

Yu, Y.-Z.; Su, H.-Y. (本科生); Zhuo, C.-X.*

Angew. Chem. Int. Ed. 2024, e202412299.



34.
Recent advances in molybdenum catalyzed asymmetric organic transformations.

Wang, J.-L.; Li, J.-T.; Wu, G.-Y.; Zhuo, C.-X.*

Trends Chem. 2024, 6, 487-501.

(Both authors contributed equally)

(Invited contribution to the Special issue: Emerging leaders in chemistry)

Highlighted by Meet our emerging leaders in chemistry – part II.Trends Chem. 2024, 6, 409-414.



33. Catalytic intermolecular deoxygenative coupling of carbonyl compounds with alkynes by a Cp*Mo(II)-catalyst.

Wang, J.-L.; Wu, G.-Y.; Luo, J.-N.; Liu, J.-L.; Zhuo, C.-X.*

J. Am. Chem. Soc. 2024, 146, 5605-5613.

(Both authors contributed equally)

Highlighted by Synfacts 2024, 20, 502.



2023

32. Modular access to diverse amphoteric α-boryl aldehydes or borylated heterocycles via photoredox catalysis.

Li, J.-T.; Fang, G.; Wu, G.-Y.; Zhuo, C.-X.*

ACS Catal. 2023, 13, 1264812655.

(Among the top 20 most downloaded articles in October 2023)



31. Molybdenum-catalyzed carbonyl-carbonyl olefination reaction for heterocycle syntheses.

Dong, Y.-Q.; Shi, X.-N.; Cao, L.-Y.; Bai, J.; Zhuo, C.-X.*

Org. Chem. Front. 2023, 10, 3544-3552.

(These authors contributed equally.)


30. Modular access to meta-substituted benzenes via Mo-catalyzed intermolecular deoxygenative benzene formation.

Yu, Y.-Z.; Bai, J.; Peng, J.-M.; Yao, J.-S.; Zhuo, C.-X.*

J. Am. Chem. Soc. 2023, 145, 8781-8787.

(Selected as JACS Supplementary Cover)

(Among the top 20 most downloaded articles in April 2023)


Highlighted by Org. Process Res. Dev. 2023, 27, 993. & Synfacts 2023, 19, 0621.



29. Synthesis of 2-boryl allylboronates by a bimetallic platinum/zinc-promoted diborylation of propargylic amines.

Shi, X.-N.; Wang, J.-L.; Wu, J.-B.; Zhuo, C.-X.*

Synlett 2023,34,1573-1574.

(Invited contribution to the Special Edition Thieme Chemistry Journals Awardees 2022)


28. Catalytic asymmetric deoxygenative cyclopropanation reactions by a chiral salen-Mo catalyst.

Cao, L.-Y.; Wang, J.-L.; Wang, K.; Wu, J.-B.; Wang, D.-K.; Peng, J.-M.; Bai, J.; Zhuo, C.-X.*

J. Am. Chem. Soc. 2023, 145, 2765-2772.

(Selected as JACS Supplementary Cover)

Highlighted by Synfacts 2023, 19, 358.




2022

27. Molybdenum-catalyzed intermolecular deoxygenative cross-coupling reactions of 1,2-diketones with α-ketoamides.

Dong, Y.-Q.; Wang, K.; Zhuo, C.-X.*

ACS Catal. 2022, 12, 11428−11435.

(Both authors contributed equally.)


26. Stereoselective intermolecular radical cascade reactions of tryptophans or ɤ-alkenyl-α-amino acids with acrylamides via photoredox catalysis.

Li, J.-T.;Luo, J.-N.;Wang, J.-L.; Wang, D.-K.; Yu, Y.-Z.; Zhuo, C.-X.*

Nat.Commun. 2022,13,1778.


2021

25. Catalytic deoxygenative cyclopropanation of 1,2-dicarbonyl or monocarbonyl compounds via molybdenum catalysis.

Wang, J.-L.; Zhuo, C.-X.*

Synlett 2022, 33, 599-608

(Invited Synpacts highlight)


24. Molybdenum-catalyzed deoxygenative cyclopropanation of 1,2-dicarbonyl or mono-carbonyl compounds.

Cao, L.-Y.; Luo, J.-N.; Yao, J.-S.; Wang, D.-K.; Dong, Y.-Q.; Zheng, C.; Zhuo, C.-X.*

Angew. Chem. Int. Ed. 2021, 60,15254–15259.

Highlighted by Nature Catalysis 2021, 4, 347. & Synfacts 2021, 17, 906.


Before XMU

23. Catalysis-based total syntheses of pateamine Aand DMDA-Pat A.

Zhuo, C.-X.;Fürstner, A.*

J. Am. Chem. Soc.2018,140,10514–10523.

Highlighted by: Synfacts  2018 , 14 , 1114.

(Among the top 20 most downloaded articles in September, 2018)


22. Concise synthesis of a pateamine A analogue with in vivo anticancer activity based on an iron catalyzed pyrone ring-opening/cross coupling.

Zhuo, C.-X.; Fürstner, A. *

Angew . Chem . Int . Ed .2016 ,55 ,6051-6056.


21. Enantioselective synthesis of pyrrole fused piperazine and piperazinone derivatives via Ir-catalyzed asymmetric allylic amination.

Zhuo, C.-X.; Zhang, X.; You, S.-L.*

ACS Catal. 2016, 6, 5307−5310.

Highlighted by: Synfacts 2016,12, 1043.


20. Enantioselective construction of spiroindolines with three contiguous stereogenic centers and chiral tryptamine derivative via the reactive spiroindolenine intermediates.

Zhuo, C.-X.; Zhou, Y.; Cheng, Q.; Huang, L.; You, S.-L.*

Angew.Chem.Int.Ed2015, 54, 14146-14149.

Highlighted by: Synfacts 2016,12, 151.


19. Enantioselective synthesis of pyrrole based spiro- and polycyclic derivatives via Ir-catalyzed asymmetric allylic dearomatization and controllable migration reactions.

Zhuo, C.-X.; Cheng, Q.; Liu, W.-B.; Zhao, Q.; You, S.-L.*

Angew.Chem.Int.Ed. 2015,54, 8475-8479.

Highlighted by: Synfacts,11, 944.


18. Highly regio- and enantioselective synthesis of poly-substituted 2H-pyrroles via Pd-catalyzed intermolecular asymmetric allylic dearomatization of pyrroles.

Zhuo, C.-X.; Zhou, Y.;You, S.-L.*

J. Am. Chem. Soc. 2014,136, 6590-6593.

Highlighted by: J. Am. Chem. Soc. Spotlights (J. Am. Chem. Soc. 2014,136, 6511.)&Synfacts 2014,10, 820.&Organic Chemistry Portal. Highlighted by the highlight module located on the homepage of JACS(May 5, 2014 – May 15, 2014.)


17. Transition-metal catalyzed asymmetric allylic dearomatization reactions.

Zhuo, C.-X.; Zheng, C.;You, S.-L.* 

Acc. Chem. Res. 2014, 47, 2558-2573.


16. Palladium-catalyzed intermolecular allylic dearomatization reaction ofa-substituted-β-naphthol derivatives: scope and mechanistic investigation.

Zhuo, C.-X.;You, S.-L.*

Adv. Synth. Catal. 2014, 356, 2020-2028.



15. Palladium-catalyzed intermolecular asymmetric allylic dearomatization reaction of naphthol derivatives. 

Zhuo, C.-X.;You, S.-L.* 

Angew.Chem.Int.Ed. 2013, 52, 10056-10059.

Highlighted by:Synfacts 2013, 9, 1308.&Chin. J. Org. Chem2013, 33, 2440.


14. Enantioselective functionalization of indoles and pyrroles via an in-situ formed spiro-intermediate. 

Zhuo, C.-X.; Wu, Q.-F; Zhao, Q.; Xu, Q.-L.; You, S.-L.* 

J. Am. Chem. Soc2013,135, 8169-8172.

Highlighted by: Synfacts 2013, 9, 874.


13. Catalytic asymmetric dearomatization reactions.

Zhuo, C.-X.; Zhang, W.*; You, S.-L.* 

Angew. Chem. Int. Ed. 2012, 51, 12662-12686.


12. Asymmetric dearomatization of pyrroles via Ir-catalyzed allylic substitution reaction: enantioselective synthesis of spiro-2H-pyrroles.

Zhuo, C.-X.; Liu, W.-B.; Wu, Q.-F.; You, S.-L.* 

Chem. Sci. 2012, 3, 205-208.


11. Mechanistic insights into the Pd-catalyzed intermolecular asymmetric allylic dearomatization of multisubstituted pyrroles: understanding the remarkable regio- and enantioselectivity.

Zheng, C.*;Zhuo, C.-X.; You, S.-L.*

J. Am. Chem. Soc. 2014, 136, 16251-16259.


10. An iridium(I) N-heterocyclic carbene complex catalyzes asymmetric intramolecular allylic amination reactions.

Ye, K.-Y.; Cheng, Q.;Zhuo, C.-X.; You, S.-L.*

Angew. Chem. Int. Ed. 2016, 55, 8113-8116.


9. Highly efficient synthesis and stereoselective migration reactions of chiral five-membered aza-spiroindolenines: scope and mechanistic understanding.

Wu, Q.-F;Zheng, C.*;Zhuo, C.-X.; You, S.-L.*

Chem. Sci. 2016,7, 4453-4459.


8. Intermolecular dearomatization reaction of pyrroles promoted by silica gel.

Zhou, Y.;Zhuo, C.-X.; Gu, Q.; You, S.-L.*

Adv. Synth. Catal. 2015,357, 912-916 (VIP).


7. Asymmetric dearomatization of β-naphthols through an amination reaction catalyzed by a chiral phosphoric acid.

Wang, S.-G.; Yin, Q.;Zhuo, C.-X.; You, S.-L.* 

Angew. Chem. Int. Ed. 2015, 54, 647-650.


 6. Ruthenium-catalyzed intramolecular allylic dearomatization/migration reaction of indoles and pyrroles.

Yang, Z.-P.;Zhuo, C.-X.; You, S.-L.*

Adv. Synth. Catal. 2014, 356, 1731-1734.


5. Enantioselective synthesis ofN-allylindoles via palladium-catalyzed allylic amination/oxidation of indolines.

Zhao, Q.;Zhuo, C.-X.; You, S.-L.*

RSC Adv. 2014, 4, 10875-10878.


4. Highly enantioselective synthesis of tetrahydrocarbolines via iridium-catalyzed intramolecular Friedel-Crafts type allylic alkylation reactions.

Xu, Q.-L.;Zhuo, C.-X.; You, S.-L.*

Org. Lett. 2013,15, 5909-5911.


3. Ir-catalyzed allylic alkylation reaction with N-aryl phosphoramidite ligands: scope and mechanistic studies.

Liu, W.-B.; Zheng, C.;Zhuo, C.-X.; Dai, L.-X.; You, S.-L.*

J. Am. Chem. Soc. 2012,134, 4812-4821.


2. Iridium-catalyzed intramolecular asymmetric allylic dearomatization of phenols.

Wu, Q.-F.; Liu, W.-B.;Zhuo, C.-X.; Rong, Z.-Q.; Ye, K.-Y.; You, S.-L.*

Angew.Chem.Int.Ed. 2011, 50, 4455-4458.


1. Synthesis of Cyclopropane-containing Building Blocks via Ir-Catalyzed Enantioselective Allylic Substitution Reaction.

Xia, J.-B.;Zhuo, C.-X.;You, S.-L.*

Chin. J. Chem. 2010, 28, 1525-1528.


Patents:

1. You, S.-L.; Zhuo, C.-X.; Liu, W.-B. Chirality phosphine nitrogen compound containing N-aryl as well as synthetic method and application thereof. CN103087106 B.